Study by Zhang et al reveals functional crosstalk between classical TAP-dependent MHC complexes and Qa-1 b /HLA-E in tumors with impaired antigen processing machinery. This can dramatically influence efficacy of immune checkpoint blockade. https://t.co/je0
Study by Zhang et al reveals functional crosstalk between classical TAP-dependent MHC complexes and Qa-1 b /HLA-E in tumors with impaired antigen processing machinery. This can dramatically influence efficacy of immune checkpoint blockade. https://t.co/lr
New from the @GeneCollector lab: resistance to anti-PD1 therapy in TAP1 deficient tumors is reversed by co-deletion of Qa-1, and is associated w/ increased CD8+ T cells and decreased tumor-associated neutrophils and CD4+ regulatory T cells: https://t.co/U
RT @GeneCollector: Qa-1b is the mouse version of HLA-E. Our study shows that this non-classical HLA modulates resistance to immune checkpo…
RT @GeneCollector: Qa-1b is the mouse version of HLA-E. Our study shows that this non-classical HLA modulates resistance to immune checkpo…
RT @GeneCollector: Qa-1b is the mouse version of HLA-E. Our study shows that this non-classical HLA modulates resistance to immune checkpo…
Congrats Tim @GeneCollector!
RT @GeneCollector: Qa-1b is the mouse version of HLA-E. Our study shows that this non-classical HLA modulates resistance to immune checkpo…
Qa-1b modulates resistance to anti-PD-1 immune checkpoint blockade in tumors with defects in antigen processing by Xiao Zhang https://t.co/e0oLYlL2wt
RT @GeneCollector: Qa-1b is the mouse version of HLA-E. Our study shows that this non-classical HLA modulates resistance to immune checkpo…
RT @GeneCollector: Qa-1b is the mouse version of HLA-E. Our study shows that this non-classical HLA modulates resistance to immune checkpo…
RT @GeneCollector: Qa-1b is the mouse version of HLA-E. Our study shows that this non-classical HLA modulates resistance to immune checkpo…
RT @GeneCollector: Qa-1b is the mouse version of HLA-E. Our study shows that this non-classical HLA modulates resistance to immune checkpo…
RT @GeneCollector: Qa-1b is the mouse version of HLA-E. Our study shows that this non-classical HLA modulates resistance to immune checkpo…
Qa-1b is the mouse version of HLA-E. Our study shows that this non-classical HLA modulates resistance to immune checkpoint therapy in tumors with defects in antigen processing. https://t.co/JC0r0QaiUl
Qa-1b modulates resistance to anti-PD-1 immune checkpoint blockade in tumors with defects in antigen processing https://t.co/YFyVMTaKTB