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American Association for Cancer Research

Article Metrics

Lysosomes as Targets for Cancer Therapy: Figure 1.

Overview of attention for article published in Cancer Research, April 2005
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
21 news outlets
twitter
2 tweeters
patent
1 patent

Citations

dimensions_citation
235 Dimensions

Readers on

mendeley
127 Mendeley
Title
Lysosomes as Targets for Cancer Therapy: Figure 1.
Published in
Cancer Research, April 2005
DOI 10.1158/0008-5472.can-05-0476
Pubmed ID
Authors

Nicole Fehrenbacher, Marja Jäättelä

Abstract

Tumor invasion and metastasis are associated with altered lysosomal trafficking and increased expression of the lysosomal proteases termed cathepsins. Emerging experimental evidence suggests that such alterations in lysosomes may form an "Achilles heel" for cancer cells by sensitizing them to death pathways involving lysosomal membrane permeabilization and the release of cathepsins into the cytosol. Here, we highlight recent results on cancer-related changes in the composition and function of lysosomes, focusing on possible implications for the development of novel cancer therapeutics that target tumor cell lysosomes.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 127 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 2 2%
United States 1 <1%
Netherlands 1 <1%
Germany 1 <1%
Unknown 122 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 31 24%
Researcher 30 24%
Student > Master 13 10%
Student > Bachelor 9 7%
Student > Doctoral Student 7 6%
Other 23 18%
Unknown 14 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 50 39%
Biochemistry, Genetics and Molecular Biology 20 16%
Chemistry 19 15%
Medicine and Dentistry 11 9%
Engineering 5 4%
Other 8 6%
Unknown 14 11%

Attention Score in Context

This research output has an Altmetric Attention Score of 147. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 June 2021.
All research outputs
#162,785
of 17,968,541 outputs
Outputs from Cancer Research
#81
of 15,650 outputs
Outputs of similar age
#2,219
of 240,066 outputs
Outputs of similar age from Cancer Research
#2
of 350 outputs
Altmetric has tracked 17,968,541 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 15,650 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,066 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 350 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.