Open Access UCL Research: Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis https://t.co/qgZwk9tR3E
ENPP1 promotes metastasis by selectively degrading extracellular cGAMP #Sting #InnateImmunity https://t.co/fIirWQkSZ6
RT @jitcancer: Dec @sitcancer #JITC Editor reading list Dr Melief @tronmainz #5 @CD_AACR Metastasis & Immune Evasion from Extracellular cGA…
RT @jitcancer: Dec @sitcancer #JITC Editor reading list Dr Melief @tronmainz #5 @CD_AACR Metastasis & Immune Evasion from Extracellular cGA…
RT @jitcancer: Dec @sitcancer #JITC Editor reading list Dr Melief @tronmainz #5 @CD_AACR Metastasis & Immune Evasion from Extracellular cGA…
RT @jitcancer: Dec @sitcancer #JITC Editor reading list Dr Melief @tronmainz #5 @CD_AACR Metastasis & Immune Evasion from Extracellular cGA…
Dec @sitcancer #JITC Editor reading list Dr Melief @tronmainz #5 @CD_AACR Metastasis & Immune Evasion from Extracellular cGAMP Hydrolysis @Samuel_Bakhoum @sloan_kettering cGAMP major contributor to adenosine in TME & ENPP1 target! https://t.co/0piS
RT @CD_AACR: From the May issue: #Metastasis and #ImmuneEvasion from extracellular #cGAMP hydrolysis. @Samuel_Bakhoum @Sloan_Kettering #Chr…
From the May issue: #Metastasis and #ImmuneEvasion from extracellular #cGAMP hydrolysis. @Samuel_Bakhoum @Sloan_Kettering #Chromosomal_Instability https://t.co/9Osnn9gWsV https://t.co/8UPWeWX39l
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
RT @Ruffell_Lab: Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum no…
Impressive study explaining the ability of cGAS to regulate both metastasis and immune suppression from @Samuel_Bakhoum now in print @CD_AACR. Explains disparate findings in the field and identifies an attractive therapeutic target in #breastcancer http
RT @ElizSMcKenna: Watching the #AACR21 Panel on Opportunities for Targeting Metastasis? ICYMI in @CD_AACR: #Metastasis and immune evasion f…
RT @ElizSMcKenna: Watching the #AACR21 Panel on Opportunities for Targeting Metastasis? ICYMI in @CD_AACR: #Metastasis and immune evasion f…
RT @ElizSMcKenna: Watching the #AACR21 Panel on Opportunities for Targeting Metastasis? ICYMI in @CD_AACR: #Metastasis and immune evasion f…
Watching the #AACR21 Panel on Opportunities for Targeting Metastasis? ICYMI in @CD_AACR: #Metastasis and immune evasion from extracellular cGAMP hydrolysis #Chromosomal_Instability @Samuel_Bakhoum @Sloan_Kettering https://t.co/rsweWVgC2d
RT @ElizSMcKenna: Read the work in @CD_AACR by @Samuel_Bakhoum and colleagues here #AACR21 https://t.co/JpZuqMUjLq https://t.co/mktYDxV1Oh
RT @ElizSMcKenna: Read the work in @CD_AACR by @Samuel_Bakhoum and colleagues here #AACR21 https://t.co/JpZuqMUjLq
RT @imsmd: .@Samuel_Bakhoum @sloan_kettering discussing the role of CIN in the immune TME at #AACR21: check out one of the papers he cited…
RT @ElizSMcKenna: Read the work in @CD_AACR by @Samuel_Bakhoum and colleagues here #AACR21 https://t.co/JpZuqMUjLq
RT @imsmd: .@Samuel_Bakhoum @sloan_kettering discussing the role of CIN in the immune TME at #AACR21: check out one of the papers he cited…
RT @ElizSMcKenna: @Samuel_Bakhoum is speaking on Chromosomal Instability and Tumor Evolution at the #AACR21 Discovery Science Plenary - rea…
RT @ElizSMcKenna: Read the work in @CD_AACR by @Samuel_Bakhoum and colleagues here #AACR21 https://t.co/JpZuqMUjLq
@Samuel_Bakhoum is speaking on Chromosomal Instability and Tumor Evolution at the #AACR21 Discovery Science Plenary - read his recent work on #Metastasis and immune evasion from extracellular cGAMP hydrolysis in @CD_AACR https://t.co/JpZuqNbUCY
RT @imsmd: .@Samuel_Bakhoum @sloan_kettering discussing the role of CIN in the immune TME at #AACR21: check out one of the papers he cited…
RT @imsmd: .@Samuel_Bakhoum @sloan_kettering discussing the role of CIN in the immune TME at #AACR21: check out one of the papers he cited…
.@Samuel_Bakhoum @sloan_kettering discussing the role of CIN in the immune TME at #AACR21: check out one of the papers he cited https://t.co/MUyWeVsuwf
RT @ElizSMcKenna: Read the work in @CD_AACR by @Samuel_Bakhoum and colleagues here #AACR21 https://t.co/JpZuqMUjLq https://t.co/mktYDxV1Oh
RT @ElizSMcKenna: Read the work in @CD_AACR by @Samuel_Bakhoum and colleagues here #AACR21 https://t.co/JpZuqMUjLq
RT @ElizSMcKenna: Read the work in @CD_AACR by @Samuel_Bakhoum and colleagues here #AACR21 https://t.co/JpZuqMUjLq https://t.co/mktYDxV1Oh
Read the work in @CD_AACR by @Samuel_Bakhoum and colleagues here #AACR21 https://t.co/JpZuqMUjLq
RT @xrtGenomics: Phenomenal work!👇👇👇
RT @CD_AACR: ICYMI: #Metastasis and immune evasion from extracellular cGAMP hydrolysis. #Chromosomal_Instability @Samuel_Bakhoum @Sloan_Ket…
RT @CD_AACR: ICYMI: #Metastasis and immune evasion from extracellular cGAMP hydrolysis. #Chromosomal_Instability @Samuel_Bakhoum @Sloan_Ket…
RT @CD_AACR: ICYMI: #Metastasis and immune evasion from extracellular cGAMP hydrolysis. #Chromosomal_Instability @Samuel_Bakhoum @Sloan_Ket…
RT @CD_AACR: ICYMI: #Metastasis and immune evasion from extracellular cGAMP hydrolysis. #Chromosomal_Instability @Samuel_Bakhoum @Sloan_Ket…
RT @CD_AACR: ICYMI: #Metastasis and immune evasion from extracellular cGAMP hydrolysis. #Chromosomal_Instability @Samuel_Bakhoum @Sloan_Ket…
RT @CD_AACR: ICYMI: #Metastasis and immune evasion from extracellular cGAMP hydrolysis. #Chromosomal_Instability @Samuel_Bakhoum @Sloan_Ket…
RT @CD_AACR: ICYMI: #Metastasis and immune evasion from extracellular cGAMP hydrolysis. #Chromosomal_Instability @Samuel_Bakhoum @Sloan_Ket…
RT @CD_AACR: ICYMI: #Metastasis and immune evasion from extracellular cGAMP hydrolysis. #Chromosomal_Instability @Samuel_Bakhoum @Sloan_Ket…
ICYMI: #Metastasis and immune evasion from extracellular cGAMP hydrolysis. #Chromosomal_Instability @Samuel_Bakhoum @Sloan_Kettering https://t.co/dNmsdUJtUE https://t.co/DHm0TY4Dnj
RT @eileen_parkes: This is an awesome paper - led by the @Samuel_Bakhoum lab & bringing together an impressive team, this paper solves the…
You can also read the paper in @AACR: https://t.co/P5O3JOT7LC
Improving response to immunotherapy: Metastasis and immune evasion from extracellular cGAMP hydrolysis https://t.co/MEb0FirVLW
RT @CD_AACR: ICYMI: #Metastasis and immune evasion from extracellular cGAMP hydrolysis. #Chromosomal_Instability @Samuel_Bakhoum @Sloan_Ke…
ICYMI: #Metastasis and immune evasion from extracellular cGAMP hydrolysis. #Chromosomal_Instability @Samuel_Bakhoum @Sloan_Kettering #AACRtme21 https://t.co/wzULuffsLC https://t.co/od4IQi6Dat
Read the study here: https://t.co/qfGGayPKNX
RT @NatRevClinOncol: Ectonucleotidase ENPP1 promotes metastasis by degrading extracellular cGAMP, an immune stimulatory metabolite whose br…
RT @NatRevClinOncol: Ectonucleotidase ENPP1 promotes metastasis by degrading extracellular cGAMP, an immune stimulatory metabolite whose br…
RT @NatRevClinOncol: Ectonucleotidase ENPP1 promotes metastasis by degrading extracellular cGAMP, an immune stimulatory metabolite whose br…
RT @NatRevClinOncol: Ectonucleotidase ENPP1 promotes metastasis by degrading extracellular cGAMP, an immune stimulatory metabolite whose br…
RT @NatRevClinOncol: Ectonucleotidase ENPP1 promotes metastasis by degrading extracellular cGAMP, an immune stimulatory metabolite whose br…
RT @NatRevClinOncol: Ectonucleotidase ENPP1 promotes metastasis by degrading extracellular cGAMP, an immune stimulatory metabolite whose br…
Ectonucleotidase ENPP1 promotes metastasis by degrading extracellular cGAMP, an immune stimulatory metabolite whose breakdown products include adenosine, thus transmuting cGAS activation in chromosomally unstable tumours into an immunosuppressive pathway:
RT @MetastasisRS: A new study on Cancer Discovery identifies a novel role of the ectonucleotidase ENPP1 in tumor cell evasion from immune s…
RT @MetastasisRS: A new study on Cancer Discovery identifies a novel role of the ectonucleotidase ENPP1 in tumor cell evasion from immune s…
RT @CD_AACR: Recently published #OnlineFirst: #Metastasis and immune evasion from extracellular cGAMP hydrolysis. #Chromosomal_Instability…
RT @MetastasisRS: A new study on Cancer Discovery identifies a novel role of the ectonucleotidase ENPP1 in tumor cell evasion from immune s…
RT @CD_AACR: Recently published #OnlineFirst: #Metastasis and immune evasion from extracellular cGAMP hydrolysis. #Chromosomal_Instability…
Recently published #OnlineFirst: #Metastasis and immune evasion from extracellular cGAMP hydrolysis. #Chromosomal_Instability @Samuel_Bakhoum @Sloan_Kettering https://t.co/iIRksEGoty https://t.co/cAxYQRdN2o
RT @MetastasisRS: A new study on Cancer Discovery identifies a novel role of the ectonucleotidase ENPP1 in tumor cell evasion from immune s…
RT @MetastasisRS: A new study on Cancer Discovery identifies a novel role of the ectonucleotidase ENPP1 in tumor cell evasion from immune s…
RT @MetastasisRS: A new study on Cancer Discovery identifies a novel role of the ectonucleotidase ENPP1 in tumor cell evasion from immune s…
RT @MetastasisRS: A new study on Cancer Discovery identifies a novel role of the ectonucleotidase ENPP1 in tumor cell evasion from immune s…
RT @MetastasisRS: A new study on Cancer Discovery identifies a novel role of the ectonucleotidase ENPP1 in tumor cell evasion from immune s…
A new study on Cancer Discovery identifies a novel role of the ectonucleotidase ENPP1 in tumor cell evasion from immune surveillance, allowing chromosomally unstable tumors to tolerate inflammation and invade distant sites. https://t.co/PHeAL5t2hp https:/
RT @david_wildtype: Targeting the STING pathway has remain elusive, with many failures in the clinic. Inhibiting ENPP1 at the surface of ca…
New research on ENPP1 supports it as great target in #cancertherapy to support checkpoint inhibitors. ENPP1 reduces cGAMP levels and blunts the immune response in the #tumor. Reducing levels on the surface of cancer cells will boost existing treatments. ht
RT @Samuel_Bakhoum: (1/n) A brief #tweetorial highlighting the key aspects of our recent paper in #Cancer Discovery @CD_AACR on how cance…
RT @LaughneyLab: How do #metastases w #CIN silence the immune-stimulatory effects of #cgas #sting signaling? Great work from the @Samuel_…
RT @kevinpunie: @OncoAlert Metastasis and immune evasion from extracellular cGAMP hydrolysis #ENPP1 👉expression inversely correlated with…
RT @kevinpunie: @OncoAlert Metastasis and immune evasion from extracellular cGAMP hydrolysis #ENPP1 👉expression inversely correlated with…
@OncoAlert Metastasis and immune evasion from extracellular cGAMP hydrolysis #ENPP1 👉expression inversely correlated with #sTILs 👉associated w/ metastasis in #TNBC 👉potential therapeutic target in chromosomal instability 👉potential biomarker for IO resp
“...{W]e didn’t understand how #cancer cells were able to survive and thrive in this #inflammatory environment.” https://t.co/nKDrKHjDc5 https://t.co/6r3yOYhKm8 https://t.co/kHUET40F0r
Check out this paper just out in @CD_AACR on the regulation of STING signalling in cancer, a collaborative work including @ParkesLab at OIRO - identifying a new immunotherapy target in chromosomally unstable cancers 👏
cGas-Sting una delle pathway più interessanti imo alla base della senescenza cellulare e implicata nel cancro 👇👇👇
RT @imsmd: Fantastic explanation of the just-published @CD_AACR paper by @Samuel_Bakhoum and colleagues!