RT @prat_aleix: 🤔similar chemical formulas + mode of action, but in the clinic we give 4.8 times more dose of ribociclib than palbociclib (…
RT @prat_aleix: 🤔similar chemical formulas + mode of action, but in the clinic we give 4.8 times more dose of ribociclib than palbociclib (…
RT @prat_aleix: 🤔similar chemical formulas + mode of action, but in the clinic we give 4.8 times more dose of ribociclib than palbociclib (…
RT @prat_aleix: 🤔similar chemical formulas + mode of action, but in the clinic we give 4.8 times more dose of ribociclib than palbociclib (…
RT @prat_aleix: 🤔similar chemical formulas + mode of action, but in the clinic we give 4.8 times more dose of ribociclib than palbociclib (…
RT @prat_aleix: 🤔similar chemical formulas + mode of action, but in the clinic we give 4.8 times more dose of ribociclib than palbociclib (…
RT @prat_aleix: 🤔similar chemical formulas + mode of action, but in the clinic we give 4.8 times more dose of ribociclib than palbociclib (…
RT @weldeiry: Thanks for sharing (you need science to make sense out of clinical data). The PK characteristics of C-max & AUC appear to ref…
Thanks for sharing (you need science to make sense out of clinical data). The PK characteristics of C-max & AUC appear to reflect the higher dosing. Interestingly the @CCR_AACR review didn’t cover the comparative PK data which I found in another refere
RT @prat_aleix: 🤔similar chemical formulas + mode of action, but in the clinic we give 4.8 times more dose of ribociclib than palbociclib (…
Interesting... can this suggest that disease progression on Palbociclib does not necessarily mean Ribociclib should be ruled out for second line treatment? #bcsm
RT @prat_aleix: 🤔similar chemical formulas + mode of action, but in the clinic we give 4.8 times more dose of ribociclib than palbociclib (…
RT @prat_aleix: 🤔similar chemical formulas + mode of action, but in the clinic we give 4.8 times more dose of ribociclib than palbociclib (…
RT @prat_aleix: 🤔similar chemical formulas + mode of action, but in the clinic we give 4.8 times more dose of ribociclib than palbociclib (…
RT @prat_aleix: 🤔similar chemical formulas + mode of action, but in the clinic we give 4.8 times more dose of ribociclib than palbociclib (…
RT @prat_aleix: 🤔similar chemical formulas + mode of action, but in the clinic we give 4.8 times more dose of ribociclib than palbociclib (…
🤔similar chemical formulas + mode of action, but in the clinic we give 4.8 times more dose of ribociclib than palbociclib (600 vs 125 mg) I wonder if this could impact their activity in particular subgroups of patients with HR+/HER2- breast cancer https: